Recherche sur l'acné et la luminothérapie

Ce ne sont que quelques travaux de recherche sur la luminothérapie, notamment la lumière bleue et rouge, comme moyen de traitement de l'acné.

Les notes sont en anglais de même que les résumés scientifiques complets.

Laser and other light therapies for the treatment of acne vulgaris: systematic review.
Br J Dermatol. 2009 Jun;160(6):1273-85.
This report summarised 25 trials (694 patients) into laser and other light therapy as a treatment for acne vulgaris. 13 of those looked at the effects of light therapy alone and trials of blue light, combination blue-red light and infrared radiation were successful, particularly with regular treatments. Combination blue-red light was shown to be more effective than topical 5% benzoyl peroxide (found in many over the counter products) in the short term.  Read the full abstract

Non-invasive diagnostic evaluation of phototherapeutic effects of red light phototherapy of acne vulgaris.
Photodermatol Photoimmunol Photomed. 2008 Oct;24(5):244-8.
Fifteen women suffering from moderate acne vulgaris were exposed to red light (600-750 nm) twice weekly for 4 weeks. Overall, there was a significant improvement in the appearance of the skin including a reduction of sebum excretion and less dryness, even at the 3-month follow-up visit. The authors concluded that red light therapy was an effective, well-tolerated, safe, simple and inexpensive treatment option for moderate acne vulgaris. Lumie Clear red LEDs emits light at 660nm. Read the full abstract

An assessment of the efficacy of blue light phototherapy in the treatment of acne vulgaris.
J Cosmet Dermatol. 2008 Sep;7(3):180-8.
This is a recent study into the effects of blue light (415-425 nm) in the treatment of acne vulgaris. 21 patients with mild to moderate facial acne were given 14-min treatment sessions twice a week for 4 weeks. Acne severity was scored before and after treatment and was seen to improve significantly and in addition this was shown to have a big impact on the patients’ quality of life. Lumie Clear has been designed using blue LEDs at 415nm. Read the full abstract

Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV.
Lasers Surg Med. 2007 Feb;39(2):180-8. 
Both blue and red light was used in this study although patients were exposed to the light treatments alternately rather than at the same time as with Lumie Clear. 24 patients with mild to moderately severe facial acne used LED devices, alternating blue (415 nm) and red (633 nm) light. At the end of the 8-week trial, skin was a lot less inflamed and - even though they weren’t specifically asked - over half those that took part said their skin looked and felt better! Read the full abstract

Light-emitting diode 415 nm in the treatment of inflammatory acne: an open-label, multicentric, pilot investigation.
J Cosmet Laser Ther. 2006 Apr;8(1):31-3.
Forty-five patients were treated with high-intensity pure blue light at 415 nm using a LED (light-emitting diode) light source. They had two 20-minute treatments a week for a period of 4-8 weeks. The treatment was well-tolerated with no side-effects and there were considerable improvements after 4 and 8 weeks, with nine patients completely clear at the end of treatment. Read the full abstract

Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris.
Br J Dermatol. 2000 May;142(5):973-8.
This was a large study involving 107 patients using blue (peak at 415 nm) and red (peaks 660 nm) light. Patients received blue light only, mixed blue and red light or cool white light (all for 15 minutes a day) or 5% benzoyl peroxide cream and were assessed every four weeks. After 12 weeks of treatment inflammation was on average 76% improved with the combined blue-red light phototherapy - better than the benzoyl peroxide cream treatment. It’s suggested that mixed blue-red light works by combining antibacterial and anti-inflammatory action. Dr Chu and the research team involved in this study have worked closely with Lumie on the development of Lumie Clear. Read the full abstract

Anti-inflammatory properties of narrow-band blue light.
J Drugs Dermatol. 2006 Jul-Aug;5(7):605-10.
Blue light (420 nm) is safe and effective in the treatment of acne vulgaris. It works because it has a toxic effect on the metabolism of Propionibacterium acnes, the bacteria responsible for the condition. This study - and others – showed blue light also had anti-inflammatory properties making it doubly useful in the treatment of acne. Read the full abstract

Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris.
J Cosmet Laser Ther. 2006 Jun;8(2):71-5. 
This was an early piece of research investigating the potential of light therapy as an alternative to conventional acne treatment. Treatment was over four weeks with subjects having two sessions a week, alternating between 415 nm blue light and 633 nm red light. The number of lesions was down after two weeks and was still down on baseline levels 8 weeks after the treatment ended. Almost all patients stuck with the treatment which was painless and had no side-effects. Read the full abstract

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